Imagine you start taking a therapeutic compound with high spirits. But then a slight inconvenience makes you entirely stop the therapy. Wouldn’t it be frustrating? Whether you are exploring TB-500 for the first time or you have been a seasoned pro in the peptide world for a long time, it is better to know all the positives and downsides to make informed health decisions. It is crucial to understand which side effects of TB-500 are common and which ones are severe so that you know what to tolerate and which needs immediate medical help. In this article, we will explore TB-500 side effects, benefits, and the factors affecting the side effects of TB-500. What is TB-500? What Does TB-500 Do? People often get confused between TB-500 and TB-4. TB-4 contains 43 amino acids and is present in limited quantities in the body. So, scientists derived the small fragment containing the most healing potential and named it TB-500 (aka thymosin beta-500). Both terms are interchangeably used, so don’t get confused; they are almost the same thing. According to a study published in Mechanisms of Ageing and Development, TB-500 speeds up the healing of muscles, bones, joints, and tendons. It holds the potential to heal multiple organs, including the liver, kidneys, heart, lungs, brain, and skin. And the healing mechanisms are pretty much the same, regardless of the organ. A review article by Annals of the New York Academy of Sciences reported that TB-500 forms blood vessels and migrates cells to the damaged area for quick recovery. This makes it particularly popular among those who play outdoor games and get frequent injuries. That’s why TB-500 is considered one of the best peptides for athletic performance. TB-500 Benefits A review article published in the Expert Opinion on Biological Therapy indicated that TB-500 is a multi-functional peptide.  Several preclinical and clinical studies have proven the TB-500 peptide benefits, as shown below: Repairs Tendons and Ligaments TB-500 peptide is best for treating tendon and ligament injuries that occur suddenly due to an accident or gradually due to repeated motion. It also alleviates wear and tear caused by aging or other medical reasons. The peptide stimulates the production of collagen (a main component of tendons), which contributes to their healing. Like other tons of happy TB-500 users, a netizen shared his tendon healing experience: Dealing with tendonitis and 7 months of debilitating tennis elbow that physiotherapy did little to help and over-the-counter painkillers were just partially numbing. 5 weeks of TB500 and BPC157 brought the pain from an 8 to a 2 and I have full range of motion now. Needless to say, it is a damn miracle and I’ll never be without it. A preclinical study published in the Regulatory Peptides revealed the effect of TB-500 on medial collateral ligament (MCL) in rats. MCL is a common ligament injury that affects knees after athletic accidents. It was observed that TB-500 treatment in rats:  Improved the stiffness and diameter of collagen fibrils Fixed the packing of the new collagen fibers Healed the injured ligament tissues Improved the function of knee joints Due to its proven tendon-repairing potential, TB-500 is categorized as one of the best peptides for tendon repair. Pro tip: Using foot arch support accelerates injury recovery. It acts as a shock absorber, aligns posture, and decreases strain on muscles, tendons, ligaments, joints, and fascia (like Achilles tendinitis and plantar fasciitis). Boosts Cardiovascular Health Based on multiple preclinical trials, a study by International Immunopharmacology suggested that TB-500 may show therapeutic potential against mild alterations in the human heart caused by aging. A netizen shared his experience with TB-500, saying: It is safe, i have proof of that being on tb500 for 6 weeks my heart was better than it was the year before i have little bad heart i did ghk-cu with it, i really recommend it. But be sure your source is legit =) During heart attack, 25 % of the cells are immediately damaged. About 0.5-1% of human heart cells tend to renew annually. However, this natural renewal rate is insufficient to compensate for the cell loss after a heart attack. That’s where TB-500 does its magic. A preclinical study published in Frontiers in Pharmacology revealed the therapeutic effect of TB-500 on the cardiac system of rats. The peptide helped in:  Preserving damaged heart tissues Preventing death of the heart cells Improving the blood-pumping ability of the heart  So, TB-500 might show a protective effect on those recovering from cardiac issues. Note: While TB-500 has heart-health benefits, if you are a heart patient, don’t use it without a doctor’s prescription. Fights Inflammation Inflammation is the root cause of several health conditions. However, TB-500 reduces inflammatory agents to fight inflammation and shows alleviative potential against multiple conditions. According to a study published in Chronic Diseases and Translational Medicine, TB-500 mitigates fatty liver disease  — a health condition associated with obesity. Another preclinical research recently published in Zagazig University Medical Journal indicated that TB-500 treatment improved the condition of rats’ lungs by: Reducing pulmonary fibrosis Decreasing inflammation Fixing the tissue structure of the lungs Also, it was suggested that TB-500 may show protective efficacy against the human disorders caused by fibrosis. Is TB-500 Safe? According to a clinical study published in the Journal of Cellular and Molecular Medicine, 30 Chinese individuals received single-dose and multi-dose treatments of TB-500. The patients showed minimal side effects. Hence, the study concluded that TB-500 is safe enough to be used in another ongoing clinical trial. However, the research on TB-500 is in preliminary stages. Its clinical efficacy for healing all human organ systems is not established yet. However, just like we cannot be 100% sure about any supplement or drug, this peptide may not work for certain health conditions despite being a miracle healing peptide. Don’t use TB-500 if you are: A cardiovascular patient Have an autoimmune disorder Face blood clotting disorder A pregnant or breastfeeding woman A cancer patient or convalescent or have a family history of