BPC-157 Dosage Calculator and Guide

Scientists and fitness communities are paying close attention to BPC-157 for its healing and inflammation-fighting potential.

Research suggests BPC-157 may help speed up wound healing, improve digestive health, and support recovery from injuries to tendons, ligaments, and muscles.

BPC-157 comes in different forms including injections, oral capsules, and nasal sprays. 

Each method delivers different amounts of the peptide to your system, which affects how well it works. This means choosing the right dosage depends on how you take it and what you’re using it for.

The challenge with BPC-157 is the lack of extensive human clinical trials, which means there are no standard dosing guidelines yet. Instead, recommendations come from laboratory studies, user experiences, and expert opinions.

Looking for help with dosing? We’ve created an interactive calculator that provides personalized dosage recommendations based on your weight and how you plan to take it.

This BPC-157 peptide calculator helps you determine weight-based doses and prepare injection solutions if needed.

BPC-157 Dosage Calculator

How to Use the Calculator

Our BPC-157 calculator offers two essential functions to help you determine your optimal protocol:

Weight-Based Dosage Calculator:

1. Enter your body weight (in kg or lbs)
2. Specify your desired dose per kg
3. The calculator will display your recommended total dose based on your parameters

Reconstitution Calculator:

1. Enter the amount of BPC-157 you have (in mg)
2. Specify the volume of bacteriostatic water you’ll use for mixing (in mL)
3. Input your target dose (in mcg)

The calculator will instantly provide:

• Your solution’s concentration (expressed in both mg/mL and mcg/mL)
• The precise volume needed to achieve your desired dose
• The equivalent measurement in insulin syringe units for accurate administration

Example: If you reconstitute 5mg of BPC-157 with 5mL of bacteriostatic water, your solution will have a concentration of 1mg/mL (1000mcg/mL). To administer a 250mcg dose, you would draw up 0.25mL, which corresponds to 25 units on a standard insulin syringe.

BPC-157 Dosage Guidelines

Dosage recommendations for BPC-157 vary based on the administration method and intended use. Below is a summary of key findings.

Standard Dosage Range

Research suggests a typical daily dosage ranges from 200 to 500 micrograms, with some protocols extending to 750mcg for initial phases of healing.

For instance, a four-week healing and repair protocol may include:

• Weeks 1-2: 500mcg-750mcg daily, administered in 2-3 injections.
• Weeks 3-4: 250mcg-500mcg daily, in 1-2 injections. This tapering approach aims to optimize healing while minimizing potential side effects.

Dosage Based on Body Weight

Several sources recommend dosing based on body weight, typically 2.5 to 3.75 micrograms per kilogram, taken twice daily. 

For example:

Body weight (kg)	2.5 micrograms/kilogram	3.75 micrograms/kilogram
60	150 micrograms	225 micrograms
70	175 micrograms	260 micrograms
80	200 micrograms	300 micrograms
90	225 micrograms	340 micrograms
100	250 micrograms	375 micrograms

This translates to a daily total of 300 to 750mcg for most adults, depending on weight and the higher end of the range.

Proposed Clinical Dose from Scientific Studies

A study published in Frontiers in Pharmacology proposes a clinical dose of 200 µg per person per day, derived from animal studies converted to human equivalents (20 μg/kg in rats, 6 μg/kg in dogs, adjusted by body surface area)¹.

This lower dose aligns with initial safety assessments but may be conservative compared to anecdotal reports.

Administration-Specific Dosing

Injections: Often recommended at 16 units (16mcg) per dose, twice daily with subcutaneous or intramuscular administration. Reconstitution with bacteriostatic water is necessary, typically achieving a 1mg/mL concentration (e.g., 5mL for 5mg vial, 0.25mL = 250mcg).

Oral Capsules: Anecdotal reports suggest ~250mcg daily, 1-3 times daily, with a maximum of 500mcg twice daily. More research is needed for safety and effectiveness.

Nasal Spray: No specific data, but doses may align with injections or oral capsules, around 200-500mcg daily, split as needed.

Combination with TB-500: For blends, a 1:1 to 1:5 ratio (TB-500 favored) is suggested, with TB-500 doses ranging from 0.5mcg/kg to higher for 10-14 days, and anecdotal starting points at 1mcg/kg daily for the combination.

Duration and Cycle

Duration recommendations include consistent daily use for up to 3 months, followed by a one-month break. This cycle allows the body to adjust and potentially reduces the risk of side effects, though long-term safety data in humans is limited.

Variability in Administration Methods

An interesting aspect is the variety of administration methods, each with different bioavailability.

For instance, intramuscular injections offer faster absorption (bioavailability ~14%-51% in animals), while oral capsules may be preferred for gut health but lack specific human data, highlighting the need for personalized approaches based on the condition being treated.

Safety and Legal Considerations

BPC-157’s safety profile is not fully understood due to limited human trials, with no clear toxicity reported in rodent studies but insufficient evidence for long-term use.

Potential side effects include nausea, headache, or fatigue at higher doses. Legally, it is not approved for human use by global regulatory authorities like the FDA, and it’s prohibited under WADA for athletes, as per USADA².

Users should consult healthcare professionals to assess liver and kidney function before starting.

Conclusion: Making Informed Decisions About BPC 157

While BPC-157 shows promising benefits in research settings for healing and recovery, it’s important to approach its use with caution and careful consideration.

The dosage guidelines outlined in this article are based on the current available research, anecdotal evidence, and expert opinions rather than standardized clinical protocols.

Before considering BPC-157, consult with a healthcare professional who can evaluate your specific health situation, potential risks, and whether this peptide might be appropriate for your needs. Remember that individual responses vary, and what works for one person may not work for another.

The calculator provided offers a starting point for those who, after careful consideration with medical guidance, decide to explore BPC-157.

Start with conservative dosages and monitor your body’s response closely. Document any effects or side effects to share with your healthcare provider.

As research continues to evolve, our understanding of optimal dosages and administration methods will likely become more refined.

Stay informed about new developments and always prioritize safety in your approach to peptide supplementation.

References

1. https://www.frontiersin.org/articles/10.3389/fphar.2022.1026182/full ↩︎
2. https://www.usada.org/spirit-of-sport/education/bpc-157-peptide-prohibited/ ↩︎